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Table 3 Top 40 proteins with reduced expression (< 0.5 fold) in C-AME, compared to F-AME

From: A cellular and proteomic approach to assess proteins extracted from cryopreserved human amnion in the cultivation of corneal stromal keratocytes for stromal cell therapy

No. UniProt Accession No. Protein Protein symbol Mean fold changes**
1 Q8WUF5 RelA-associated inhibitor PPP1R13L 0.010
2 P58215 Lysyl oxidase homolog 3 LOXL3 0.040
3 P20774 Mimecan OGN 0.052
4 P07355 Annexin A2 ANXA2 0.057
5 O95171 Sciellin SCEL 0.069
6 P51991 Heterogeneous nuclear ribonucleoprotein A3 HNRNPA3 0.081
7 P07203 Glutathione peroxidase 1 GPX1 0.092
8 P09429 High mobility group protein B1 HMGB1 0.098
9 O76041 Nebulette NEBL 0.100
10 P09525 Annexin A4 ANXA4 0.111
11 P63244 Receptor of activated protein C kinase 1 RACK1 0.112
12 P60174 Triosephosphate isomerase TPI1 0.113
13 Q9UBC9 Small proline-rich protein 3 SPRR3 0.114
14 P23497 Nuclear autoantigen Sp-100 SP100 0.128
15 O15231 Zinc finger protein 185 ZNF185 0.129
16 P0DMV9 Heat shock 70 kDa protein 1B HSPA1B 0.130
17 Q92541 RTF1 Homolog, Paf1/RNA Polymerase II Complex Component RTF1 0.131
18 Q8NC51 Plasminogen activator inhibitor 1 RNA-binding protein SERBP1 0.134
19 P00338 L-lactate dehydrogenase A LDHA 0.134
20 O43768 Alpha-endosulfine ENSA 0.135
21 Q9GZT8 NGG1 Interacting Factor 3 Like 1 NIF3L1 0.136
22 P07858 Cathepsin B CTSB 0.137
23 P20810 Calpastatin CAST 0.138
24 P00558 Phosphoglycerate kinase 1 PGK1 0.139
25 P56211 cAMP-regulated phosphoprotein 19 ARPP19 0.140
26 Q9P258 Regulator of Chromosome Condensation 2 RCC2 0.147
27 P50238 Cysteine-rich protein 1 CRIP1 0.148
28 P60903 Protein S100-A10 S100A10 0.149
29 P62937 Peptidyl-prolyl cis-trans isomerase A PPIA 0.150
30 P04075 Fructose-bisphosphate aldolase A ALDOA 0.151
31 Q01469 Fatty acid-binding protein FABP5 0.156
32 P31939 Bifunctional purine biosynthesis protein PURH ATIC 0.158
33 P12277 Creatine kinase B-type CKB 0.158
34 P00441 Superoxide dismutase [Cu-Zn] SOD1 0.161
35 Q8WWI1 LIM domain only protein 7 LMO7 0.163
36 P06733 Alpha-enolase ENO1 0.164
37 O75083 WD repeat-containing protein 1 WDR1 0.166
38 P10915 Hyaluronan and proteoglycan link protein 1 HAPLN1 0.167
39 O43399 Tumour Protein D52 Like 2 TPD52L2 0.168
40 P09211 Glutathione S-transferase P GSTP1 0.169
  1. F-AME = fresh human amnion extract, C-AME = cryopreserved human amnion extract
  2. *The protein list was ranked by mean fold changes from all 3 amnion samples
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Eye and Vision

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